Custom siRNA Synthesis for Therapeutic Research

TriLink's range of services include custom siRNA synthesis for use in therapeutic research. TriLink custom oligonucleotides have been and continue to be instrumental in the discovery and development of new DNA and RNA based therapies. Custom synthesized oligonucleotides may be produced with full document control and in a QSR environment, as required by the end user.

A leader in the production of custom oligonucleotides for clinical and pre-clinical research, TriLink's modified RNA oligonucleotides and other derivatives are known for their high quality, which is ensured by TriLink's stringent quality control procedures, including HPLC and/or MS as well PAGE analysis of every product produced by the company.

Additional analysis and purification procedures are also available as needed, including aliquotting and annealing. Batches of up to 10 grams may be synthesized, according to the needs of clients.

RNAi's role in the latest generations of therapy have made oligonucleotides in high demand for clinical research and pharmaceutical development applications.

TriLink is a leader in the synthesis of custom synthetic RNAi oligonucleotides which show great promise in their ability to silence genes in specific sequences; an area which is increasingly important to drug development and genetic research.

In order to comply with FDA investigative new drug (IND) regulations, TriLink provides radioactive labeling of phosphorothioate and phosphodiester oligonucleotides. With a standard of purity higher than 90% (and often above 95%), TriLink custom synthesized oligonucleotides are ideal for pre-clinical trials and other research and development applications.

Date added: 2012-05-03 16:39:01